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Klf5 Deletion Promotes Pten Deletion–Initiated Luminal-Type Mouse Prostate Tumors through Multiple Oncogenic Signaling Pathways()()
Krüppel-like factor 5 (KLF5) regulates multiple biologic processes. Its function in tumorigenesis appears contradictory though, showing both tumor suppressor and tumor promoting activities. In this study, we examined whether and how Klf5 functions in prostatic tumorigenesis using mice with prostate-...
Autores principales: | Xing, Changsheng, Ci, Xinpei, Sun, Xiaodong, Fu, Xiaoying, Zhang, Zhiqian, Dong, Eric N., Hao, Zhao-Zhe, Dong, Jin-Tang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4240924/ https://www.ncbi.nlm.nih.gov/pubmed/25425963 http://dx.doi.org/10.1016/j.neo.2014.09.006 |
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