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Multimodal antidepressant vortioxetine increases frontal cortical oscillations unlike escitalopram and duloxetine – a quantitative EEG study in rats

BACKGROUND AND PURPOSE: EEG studies show that 5-HT is involved in regulation of sleep–wake state and modulates cortical oscillations. Vortioxetine is a 5-HT(3), 5-HT(7), and 5-HT(1D) receptor antagonist, 5-HT(1B) partial agonist, 5-HT(1A) agonist, and 5-HT transporter inhibitor. Preclinical (animal)...

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Detalles Bibliográficos
Autores principales:	Leiser, S C, Pehrson, A L, Robichaud, P J, Sanchez, C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2014
Materias:	Research Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4241092/ https://www.ncbi.nlm.nih.gov/pubmed/24846338 http://dx.doi.org/10.1111/bph.12782

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