Cargando…

Voltage Sensor Gating Charge Transfer in a hERG Potassium Channel Model

Relaxation of a hERG K(+) channel model during molecular-dynamics simulation in a hydrated POPC bilayer was accompanied by transitions of an arginine gating charge across a charge transfer center in two voltage sensor domains. Inspection of the passage of arginine side chains across the charge trans...

Descripción completa

Detalles Bibliográficos
Autores principales: Colenso, Charlotte K., Cao, Yang, Sessions, Richard B., Hancox, Jules C., Dempsey, Christopher E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4241455/
https://www.ncbi.nlm.nih.gov/pubmed/25418316
http://dx.doi.org/10.1016/j.bpj.2014.10.001