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MycN promotes TRPM7 expression and cell migration in neuroblastoma through a process that involves polyamines

Neuroblastoma is an extra-cranial solid cancer in children. MYCN gene amplification is a prognostic indicator of poor outcome in neuroblastoma. Recent studies have shown that the multiple steps involved in cell migration are dependent on the availability of intracellular calcium (Ca(2+)). Although s...

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Detalles Bibliográficos
Autores principales: Lange, Ingo, Koomoa, Dana-Lynn T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4241534/
https://www.ncbi.nlm.nih.gov/pubmed/25426416
http://dx.doi.org/10.1016/j.fob.2014.10.012