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Synthesis of novel bioactive lactose-derived oligosaccharides by microbial glycoside hydrolases

Prebiotic oligosaccharides are increasingly demanded within the Food Science domain because of the interesting healthy properties that these compounds may induce to the organism, thanks to their beneficial intestinal microbiota growth promotion ability. In this regard, the development of new efficie...

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Detalles Bibliográficos
Autores principales: Díez-Municio, Marina, Herrero, Miguel, Olano, Agustín, Moreno, F Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4241725/
https://www.ncbi.nlm.nih.gov/pubmed/24690139
http://dx.doi.org/10.1111/1751-7915.12124
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author Díez-Municio, Marina
Herrero, Miguel
Olano, Agustín
Moreno, F Javier
author_facet Díez-Municio, Marina
Herrero, Miguel
Olano, Agustín
Moreno, F Javier
author_sort Díez-Municio, Marina
collection PubMed
description Prebiotic oligosaccharides are increasingly demanded within the Food Science domain because of the interesting healthy properties that these compounds may induce to the organism, thanks to their beneficial intestinal microbiota growth promotion ability. In this regard, the development of new efficient, convenient and affordable methods to obtain this class of compounds might expand even further their use as functional ingredients. This review presents an overview on the most recent interesting approaches to synthesize lactose-derived oligosaccharides with potential prebiotic activity paying special focus on the microbial glycoside hydrolases that can be effectively employed to obtain these prebiotic compounds. The most notable advantages of using lactose-derived carbohydrates such as lactosucrose, galactooligosaccharides from lactulose, lactulosucrose and 2-α-glucosyl-lactose are also described and commented.
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spelling pubmed-42417252014-12-08 Synthesis of novel bioactive lactose-derived oligosaccharides by microbial glycoside hydrolases Díez-Municio, Marina Herrero, Miguel Olano, Agustín Moreno, F Javier Microb Biotechnol Research Articles Prebiotic oligosaccharides are increasingly demanded within the Food Science domain because of the interesting healthy properties that these compounds may induce to the organism, thanks to their beneficial intestinal microbiota growth promotion ability. In this regard, the development of new efficient, convenient and affordable methods to obtain this class of compounds might expand even further their use as functional ingredients. This review presents an overview on the most recent interesting approaches to synthesize lactose-derived oligosaccharides with potential prebiotic activity paying special focus on the microbial glycoside hydrolases that can be effectively employed to obtain these prebiotic compounds. The most notable advantages of using lactose-derived carbohydrates such as lactosucrose, galactooligosaccharides from lactulose, lactulosucrose and 2-α-glucosyl-lactose are also described and commented. BlackWell Publishing Ltd 2014-07 2014-04-01 /pmc/articles/PMC4241725/ /pubmed/24690139 http://dx.doi.org/10.1111/1751-7915.12124 Text en © 2014 The Authors. Microbial Biotechnology published by John Wiley & Sons Ltd and Society for Applied Microbiology. http://creativecommons.org/licenses/by/3.0/ This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Articles
Díez-Municio, Marina
Herrero, Miguel
Olano, Agustín
Moreno, F Javier
Synthesis of novel bioactive lactose-derived oligosaccharides by microbial glycoside hydrolases
title Synthesis of novel bioactive lactose-derived oligosaccharides by microbial glycoside hydrolases
title_full Synthesis of novel bioactive lactose-derived oligosaccharides by microbial glycoside hydrolases
title_fullStr Synthesis of novel bioactive lactose-derived oligosaccharides by microbial glycoside hydrolases
title_full_unstemmed Synthesis of novel bioactive lactose-derived oligosaccharides by microbial glycoside hydrolases
title_short Synthesis of novel bioactive lactose-derived oligosaccharides by microbial glycoside hydrolases
title_sort synthesis of novel bioactive lactose-derived oligosaccharides by microbial glycoside hydrolases
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4241725/
https://www.ncbi.nlm.nih.gov/pubmed/24690139
http://dx.doi.org/10.1111/1751-7915.12124
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