Central Memory CD4(+) T Cells Are Responsible for the Recombinant Bacillus Calmette-Guérin ΔureC::hly Vaccine's Superior Protection Against Tuberculosis

Bacillus Calmette-Guérin (BCG) has been used for vaccination against tuberculosis for nearly a century. Here, we analyze immunity induced by a live tuberculosis vaccine candidate, recombinant BCG ΔureC::hly vaccine (rBCG), with proven preclinical and clinical safety and immunogenicity. We pursue in-...

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Detalles Bibliográficos
Autores principales: Vogelzang, Alexis, Perdomo, Carolina, Zedler, Ulrike, Kuhlmann, Stefanie, Hurwitz, Robert, Gengenbacher, Martin, Kaufmann, Stefan H. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Major Articles and Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4241943/
https://www.ncbi.nlm.nih.gov/pubmed/24943726
http://dx.doi.org/10.1093/infdis/jiu347

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