Extracellular Vesicles in Heart Disease: Excitement for the Future ?

Extracellular vesicles (EV), including exosomes, microvesicles and apoptotic bodies, are released from numerous cell types and are involved in intercellular communication, physiological functions and the pathology of disease. They have been shown to carry and transfer a wide range of cargo including...

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Detalles Bibliográficos
Autores principales: Danielson, Kirsty M., Das, Saumya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4242103/
https://www.ncbi.nlm.nih.gov/pubmed/25429310
http://dx.doi.org/10.5772/58390
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author Danielson, Kirsty M.
Das, Saumya
author_facet Danielson, Kirsty M.
Das, Saumya
author_sort Danielson, Kirsty M.
collection PubMed
description Extracellular vesicles (EV), including exosomes, microvesicles and apoptotic bodies, are released from numerous cell types and are involved in intercellular communication, physiological functions and the pathology of disease. They have been shown to carry and transfer a wide range of cargo including proteins, lipids and nucleic acids. The role of EVs in cardiac physiology and heart disease is an emerging field that has produced intriguing findings in recent years. This review will outline what is currently known about EVs in the cardiovascular system, including cellular origins, functional roles and utility as biomarkers and potential therapeutics.
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spelling pubmed-42421032014-11-24 Extracellular Vesicles in Heart Disease: Excitement for the Future ? Danielson, Kirsty M. Das, Saumya Exosomes Microvesicles Article Extracellular vesicles (EV), including exosomes, microvesicles and apoptotic bodies, are released from numerous cell types and are involved in intercellular communication, physiological functions and the pathology of disease. They have been shown to carry and transfer a wide range of cargo including proteins, lipids and nucleic acids. The role of EVs in cardiac physiology and heart disease is an emerging field that has produced intriguing findings in recent years. This review will outline what is currently known about EVs in the cardiovascular system, including cellular origins, functional roles and utility as biomarkers and potential therapeutics. 2014 /pmc/articles/PMC4242103/ /pubmed/25429310 http://dx.doi.org/10.5772/58390 Text en © 2014 The Author(s). License InTech. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Article
Danielson, Kirsty M.
Das, Saumya
Extracellular Vesicles in Heart Disease: Excitement for the Future ?
title Extracellular Vesicles in Heart Disease: Excitement for the Future ?
title_full Extracellular Vesicles in Heart Disease: Excitement for the Future ?
title_fullStr Extracellular Vesicles in Heart Disease: Excitement for the Future ?
title_full_unstemmed Extracellular Vesicles in Heart Disease: Excitement for the Future ?
title_short Extracellular Vesicles in Heart Disease: Excitement for the Future ?
title_sort extracellular vesicles in heart disease: excitement for the future ?
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4242103/
https://www.ncbi.nlm.nih.gov/pubmed/25429310
http://dx.doi.org/10.5772/58390
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