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Inactivation of RARβ inhibits Wnt1-induced mammary tumorigenesis by suppressing epithelial-mesenchymal transition
Retinoic acid receptor β (RARβ) has been proposed to act as a tumor suppressor in breast cancer. In contrast, recent data have shown that RARβ promotes ERBB2-induced mammary gland tumorigenesis through remodeling of the stromal compartment and activation of cancer-associated fibroblasts. However, it...
Autores principales: | Liu, Xingxing, Giguère, Vincent |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nuclear Receptor Signaling Atlas
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4242291/ https://www.ncbi.nlm.nih.gov/pubmed/25422594 http://dx.doi.org/10.1621/nrs.12004 |
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