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Affecting Pseudomonas aeruginosa Phenotypic Plasticity by Quorum Sensing Dysregulation Hampers Pathogenicity in Murine Chronic Lung Infection
In Pseudomonas aeruginosa quorum sensing (QS) activates the production of virulence factors, playing a critical role in pathogenesis. Multiple negative regulators modulate the timing and the extent of the QS response either in the pre-quorum or post-quorum phases of growth. This regulation likely in...
Autores principales: | Bondí, Roslen, Messina, Marco, De Fino, Ida, Bragonzi, Alessandra, Rampioni, Giordano, Leoni, Livia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4242533/ https://www.ncbi.nlm.nih.gov/pubmed/25420086 http://dx.doi.org/10.1371/journal.pone.0112105 |
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