Cargando…
TRPV1 antagonist attenuates postoperative hypersensitivity by central and peripheral mechanisms
BACKGROUND: Acute postoperative pain is one of the frequent reasons for pain treatment. However, the exact mechanisms of its development are still not completely clear. Transient receptor potential vanilloid 1 (TRPV1) receptors are involved in nociceptive signaling in various hypersensitive states....
Autores principales: | Uchytilova, Eva, Spicarova, Diana, Palecek, Jiri |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4242597/ https://www.ncbi.nlm.nih.gov/pubmed/25403542 http://dx.doi.org/10.1186/1744-8069-10-67 |
Ejemplares similares
-
Hypersensitivity Induced by Intrathecal Bradykinin Administration Is Enhanced by N-oleoyldopamine (OLDA) and Prevented by TRPV1 Antagonist
por: Uchytilova, Eva, et al.
Publicado: (2021) -
Hypersensitivity Induced by Activation of Spinal Cord PAR2 Receptors Is Partially Mediated by TRPV1 Receptors
por: Mrozkova, Petra, et al.
Publicado: (2016) -
Spinal PAR2 Activation Contributes to Hypersensitivity Induced by Peripheral Inflammation in Rats
por: Mrozkova, Petra, et al.
Publicado: (2021) -
Tumor necrosis factor α sensitizes spinal cord TRPV1 receptors to the endogenous agonist N-oleoyldopamine
por: Spicarova, Diana, et al.
Publicado: (2010) -
Modulation of spinal cord synaptic activity by tumor necrosis factor α in a model of peripheral neuropathy
por: Spicarova, Diana, et al.
Publicado: (2011)