Cargando…

Proteomic Analysis of the Effects of Aged Garlic Extract and Its FruArg Component on Lipopolysaccharide-Induced Neuroinflammatory Response in Microglial Cells

Aged garlic extract (AGE) is widely used as a dietary supplement, and is claimed to promote human health through anti-oxidant/anti-inflammatory activities with hypolipidemic, antiplatelet and neuroprotective effects. Prior studies of AGE have mainly focused on its organosulfur compounds, with little...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhou, Hui, Qu, Zhe, Mossine, Valeri V., Nknolise, Dineo L., Li, Jilong, Chen, Zhenzhou, Cheng, Jianlin, Greenlief, C. Michael, Mawhinney, Thomas P., Brown, Paula N., Fritsche, Kevin L., Hannink, Mark, Lubahn, Dennis B., Sun, Grace Y., Gu, Zezong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4242640/ https://www.ncbi.nlm.nih.gov/pubmed/25420111 http://dx.doi.org/10.1371/journal.pone.0113531

Ejemplares similares

Effects of aged garlic extract and FruArg on gene expression and signaling pathways in lipopolysaccharide-activated microglial cells
por: Song, Hailong, et al.
Publicado: (2016)

Development of a Method and Validation for the Quantitation of FruArg in Mice Plasma and Brain Tissue Using UPLC–MS/MS
por: Johnson, Mitch C., et al.
Publicado: (2016)

Bioactive components from garlic on brain resiliency against neuroinflammation and neurodegeneration
por: Song, Hailong, et al.
Publicado: (2020)

NitroDIGE analysis reveals inhibition of protein S-nitrosylation by epigallocatechin gallates in lipopolysaccharide-stimulated microglial cells
por: Qu, Zhe, et al.
Publicado: (2014)

From Gigabyte to Kilobyte: A Bioinformatics Protocol for Mining Large RNA-Seq Transcriptomics Data
por: Li, Jilong, et al.
Publicado: (2015)

piggyBac Transposon plus Insulators Overcome Epigenetic Silencing to Provide for Stable Signaling Pathway Reporter Cell Lines
por: Mossine, Valeri V., et al.
Publicado: (2013)

Microglia Signaling Pathway Reporters Unveiled Manganese Activation of the Interferon/STAT1 Pathway and Its Mitigation by Flavonoids
por: Mossine, Valeri V., et al.
Publicado: (2023)

HPr prevents FruR-mediated facilitation of RNA polymerase binding to the fru promoter in Vibrio cholerae
por: Yoon, Chang-Kyu, et al.
Publicado: (2023)

Vibrio cholerae FruR facilitates binding of RNA polymerase to the fru promoter in the presence of fructose 1-phosphate
por: Yoon, Chang-Kyu, et al.
Publicado: (2021)

Proteomic Quantification and Site-Mapping of S-Nitrosylated Proteins Using Isobaric iodoTMT Reagents
por: Qu, Zhe, et al.
Publicado: (2014)

Unveiling anti-oxidative and anti-inflammatory effects of docosahexaenoic acid and its lipid peroxidation product on lipopolysaccharide-stimulated BV-2 microglial cells
por: Yang, Bo, et al.
Publicado: (2018)

Quercetin Potentiates Docosahexaenoic Acid to Suppress Lipopolysaccharide-induced Oxidative/Inflammatory Responses, Alter Lipid Peroxidation Products, and Enhance the Adaptive Stress Pathways in BV-2 Microglial Cells
por: Sun, Grace Y., et al.
Publicado: (2019)

Crystal structure of the acyclic form of 1-deoxy-1-[(4-methoxyphenyl)(methyl)amino]-d-fructose
por: Mossine, Valeri V., et al.
Publicado: (2018)

Crystal structure and hydrogen bonding in N-(1-deoxy-β-d-fructopyranos-1-yl)-2-aminoisobutyric acid
por: Mossine, Valeri V., et al.
Publicado: (2018)

Multicentered hydrogen bonding in 1-[(1-deoxy-β-d-fructopyranos-1-yl)azaniumyl]cyclopentanecarboxylate (‘d-fructose-cycloleucine’)
por: Mossine, Valeri V., et al.
Publicado: (2019)

Dried Fruit Intake and Cancer: A Systematic Review of Observational Studies
por: Mossine, Valeri V, et al.
Publicado: (2020)

Intramolecular 1,5-S⋯N σ-hole interaction in (E)-N′-(pyridin-4-ylmethylidene)thiophene-2-carbohydrazide
por: Mossine, Valeri V., et al.
Publicado: (2020)

β-d-Galactopyranosyl-(1→4)–2-amino-2-deoxy-α-d-glucopyranose hydrochloride monohydrate (lactosamine)
por: Mossine, Valeri V., et al.
Publicado: (2022)

4-(Dimethylamino)benzohydrazide
por: Kelley, Steven P., et al.
Publicado: (2020)

2-Bromo-6-hydrazinylpyridine
por: Mossine, Valeri V., et al.
Publicado: (2023)

Hot-plug Based Activation and Deactivation of ATCA FRU Devices
por: Predki, P, et al.
Publicado: (2009)

Magnolia polyphenols attenuate oxidative and inflammatory responses in neurons and microglial cells
por: Chuang, Dennis Y, et al.
Publicado: (2013)

Effects of Paeonol on Anti-Neuroinflammatory Responses in Microglial Cells
por: Lin, Chingju, et al.
Publicado: (2015)

Sutherlandia frutescens Ethanol Extracts Inhibit Oxidative Stress and Inflammatory Responses in Neurons and Microglial Cells
por: Jiang, Jinghua, et al.
Publicado: (2014)

RAFT-based tri-component fluorescent glycopolymers: synthesis, characterization and application in lectin-mediated bacterial binding study
por: Wang, Wei, et al.
Publicado: (2013)

Genes targeted by the Hedgehog-signaling pathway can be regulated by Estrogen related receptor β
por: Lu, Yuan, et al.
Publicado: (2015)

Messenger RNA profile analysis deciphers new Esrrb responsive genes in prostate cancer cells
por: Lu, Yuan, et al.
Publicado: (2015)

The flavonoid agathisflavone modulates the microglial neuroinflammatory response and enhances remyelination
por: de Almeida, Monique Marylin Alves, et al.
Publicado: (2020)

Transient Proteotoxicity of Bacterial Virulence Factor Pyocyanin in Renal Tubular Epithelial Cells Induces ER-Related Vacuolation and Can Be Efficiently Modulated by Iron Chelators
por: Mossine, Valeri V., et al.
Publicado: (2016)

Interaction of Bacterial Phenazines with Colistimethate in Bronchial Epithelial Cells
por: Mossine, Valeri V., et al.
Publicado: (2018)

Transient Proteotoxicity of Bacterial Virulence Factor Pyocyanin in Renal Tubular Epithelial Cells Induces ER-Related Vacuolation and Can Be Efficiently Modulated by Iron Chelators
por: Mossine, Valeri V., et al.
Publicado: (2017)

Structure, Antioxidant and Anti-inflammatory Activities of the (4R)- and (4S)-epimers of S-Carboxymethyl-L-cysteine Sulfoxide
por: Waters, James K., et al.
Publicado: (2020)

Structural and Functional Studies of S-(2-Carboxyethyl)-L-Cysteine and S-(2-Carboxyethyl)-l-Cysteine Sulfoxide
por: Waters, James K., et al.
Publicado: (2022)

Evaluating the Anti-Neuroinflammatory Capacity of Raw and Steamed Garlic as Well as Five Organosulfur Compounds
por: Ho, Su-Chen, et al.
Publicado: (2014)

Quercetin Attenuates Inflammatory Responses in BV-2 Microglial Cells: Role of MAPKs on the Nrf2 Pathway and Induction of Heme Oxygenase-1
por: Sun, Grace Y., et al.
Publicado: (2015)

Dietary Sutherlandia and Elderberry Mitigate Cerebral Ischemia-Induced Neuronal Damage and Attenuate p47phox and Phospho-ERK1/2 Expression in Microglial Cells
por: Chuang, Dennis Y., et al.
Publicado: (2014)

Quantitative Proteomics Reveals Docosahexaenoic Acid-Mediated Neuroprotective Effects in Lipopolysaccharide-Stimulated Microglial Cells
por: Yang, Bo, et al.
Publicado: (2020)

Role of FruR transcriptional regulator in virulence of Listeria monocytogenes and identification of its regulon
por: Abdelhamed, Hossam, et al.
Publicado: (2022)

Crystal structure of (R,S)-2-hydroxy-4-(methylsulfanyl)butanoic acid
por: Mawhinney, Thomas P., et al.
Publicado: (2020)

Ashwagandha attenuates TNF-α- and LPS-induced NF-κB activation and CCL2 and CCL5 gene expression in NRK-52E cells
por: Grunz-Borgmann, Elizabeth, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_rb4kg5n1vid700bj0nqef5conm