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Tumor Necrosis Factor-α Sensitizes Breast Cancer Cells to Natural Products with Proteasome-Inhibitory Activity Leading to Apoptosis
The inflammatory microenvironment plays an important role in the process of tumor development. Tumor necrosis factor-α (TNF-α), a key pro-inflammatory cytokine, has a significant role in this process. Natural medicinal products such as Withaferin A (WA) and Celastrol (Cel) have shown anti-cancer and...
Autores principales: | Lu, Li, Shi, Wenli, Deshmukh, Rahul R., Long, Jie, Cheng, Xiaoli, Ji, Weidong, Zeng, Guohua, Chen, Xianliang, Zhang, Yajie, Dou, Q. Ping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4242672/ https://www.ncbi.nlm.nih.gov/pubmed/25419573 http://dx.doi.org/10.1371/journal.pone.0113783 |
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