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Identification of Transglutaminase Reactive Residues in Human Osteopontin and Their Role in Polymerization
Osteopontin (OPN) is a highly posttranslationally modified protein present in several tissues where it is implicated in numerous physiological processes. OPN primarily exerts its functions through interaction with integrins via the Arg-Gly-Asp and Ser-Val-Val-Tyr-Gly-Leu-Arg sequences located in the...
Autores principales: | Christensen, Brian, Zachariae, Elias D., Scavenius, Carsten, Thybo, Morten, Callesen, Morten M., Kløverpris, Søren, Oxvig, Claus, Enghild, Jan J., Sørensen, Esben S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4242673/ https://www.ncbi.nlm.nih.gov/pubmed/25419572 http://dx.doi.org/10.1371/journal.pone.0113650 |
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