Stargazin promotes closure of the AMPA receptor ligand-binding domain

Transmembrane AMPA receptor (AMPAR) regulatory proteins (TARPs) markedly enhance AMPAR function, altering ligand efficacy and receptor gating kinetics and thereby shaping the postsynaptic response. The structural mechanism underlying TARP effects on gating, however, is unknown. Here we find that the...

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Detalles Bibliográficos
Autores principales: MacLean, David M., Ramaswamy, Swarna S., Du, Mei, Howe, James R., Jayaraman, Vasanthi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4242809/
https://www.ncbi.nlm.nih.gov/pubmed/25422502
http://dx.doi.org/10.1085/jgp.201411287

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4242809/
https://www.ncbi.nlm.nih.gov/pubmed/25422502
http://dx.doi.org/10.1085/jgp.201411287

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