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Crystal structure of the sodium–proton antiporter NhaA dimer and new mechanistic insights

Sodium–proton antiporters rapidly exchange protons and sodium ions across the membrane to regulate intracellular pH, cell volume, and sodium concentration. How ion binding and release is coupled to the conformational changes associated with transport is not clear. Here, we report a crystal form of t...

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Detalles Bibliográficos
Autores principales:	Lee, Chiara, Yashiro, Shoko, Dotson, David L., Uzdavinys, Povilas, Iwata, So, Sansom, Mark S.P., von Ballmoos, Christoph, Beckstein, Oliver, Drew, David, Cameron, Alexander D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2014
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4242812/ https://www.ncbi.nlm.nih.gov/pubmed/25422503 http://dx.doi.org/10.1085/jgp.201411219

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