STIM1- and Orai1-mediated Ca(2+) oscillation orchestrates invadopodium formation and melanoma invasion

Ca(2+) signaling has been increasingly implicated in cancer invasion and metastasis, and yet, the underlying mechanisms remained largely unknown. In this paper, we report that STIM1- and Orai1-mediated Ca(2+) oscillations promote melanoma invasion by orchestrating invadopodium assembly and extracell...

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Detalles Bibliográficos
Autores principales: Sun, Jianwei, Lu, Fujian, He, Huifang, Shen, Junling, Messina, Jane, Mathew, Rahel, Wang, Dapeng, Sarnaik, Amod A., Chang, Wei-Chiao, Kim, Minjung, Cheng, Heping, Yang, Shengyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4242838/
https://www.ncbi.nlm.nih.gov/pubmed/25404747
http://dx.doi.org/10.1083/jcb.201407082

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