Prolonged use of a proton pump inhibitor reduces microbial diversity: implications for Clostridium difficile susceptibility

BACKGROUND: The role of the gut microbiome in arresting pathogen colonization and growth is important for protection against Clostridium difficile infection (CDI). Observational studies associate proton pump inhibitor (PPI) use and CDI incidence. We hypothesized that PPI use affected the distal gut...

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Detalles Bibliográficos
Autores principales: Seto, Charlie T, Jeraldo, Patricio, Orenstein, Robert, Chia, Nicholas, DiBaise, John K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4242847/
https://www.ncbi.nlm.nih.gov/pubmed/25426290
http://dx.doi.org/10.1186/2049-2618-2-42

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