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Successful HLA haploidentical myeloablative stem cell transplantation for aggressive hepatosplenic alpha/beta (αβ) T-cell lymphoma

Hepatosplenic T cell lymphoma (HSTCL) is a type of hematologic neoplasia with a poor prognosis and a high frequency of refractoriness to conventional chemotherapy. The results obtained by high dose chemotherapy followed by autologous stem cells transplantation seem to be a more effective option but...

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Autores principales: Catania, Gioacchino, Zallio, Francesco, Monaco, Federico, Corsetti, Maria Teresa, Trincheri, Nicol, Bonello, Lisa, Mele, Lia, Dallavalle, Franco, Salvi, Flavia, Pini, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4242978/
https://www.ncbi.nlm.nih.gov/pubmed/25429355
http://dx.doi.org/10.1016/j.lrr.2014.09.001
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author Catania, Gioacchino
Zallio, Francesco
Monaco, Federico
Corsetti, Maria Teresa
Trincheri, Nicol
Bonello, Lisa
Mele, Lia
Dallavalle, Franco
Salvi, Flavia
Pini, Massimo
author_facet Catania, Gioacchino
Zallio, Francesco
Monaco, Federico
Corsetti, Maria Teresa
Trincheri, Nicol
Bonello, Lisa
Mele, Lia
Dallavalle, Franco
Salvi, Flavia
Pini, Massimo
author_sort Catania, Gioacchino
collection PubMed
description Hepatosplenic T cell lymphoma (HSTCL) is a type of hematologic neoplasia with a poor prognosis and a high frequency of refractoriness to conventional chemotherapy. The results obtained by high dose chemotherapy followed by autologous stem cells transplantation seem to be a more effective option but still unsatisfactory. Also the role of allogeneic stem cell transplantation is still unclear, although the few cases reported on the literature would seem to show good results in overall survival rates. In this paper, we reported the patient׳s medical history affected by a αβ variant of hepatosplenic T cell successfully rescued with a haploidentical transplant.
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spelling pubmed-42429782014-11-26 Successful HLA haploidentical myeloablative stem cell transplantation for aggressive hepatosplenic alpha/beta (αβ) T-cell lymphoma Catania, Gioacchino Zallio, Francesco Monaco, Federico Corsetti, Maria Teresa Trincheri, Nicol Bonello, Lisa Mele, Lia Dallavalle, Franco Salvi, Flavia Pini, Massimo Leuk Res Rep Case Report Hepatosplenic T cell lymphoma (HSTCL) is a type of hematologic neoplasia with a poor prognosis and a high frequency of refractoriness to conventional chemotherapy. The results obtained by high dose chemotherapy followed by autologous stem cells transplantation seem to be a more effective option but still unsatisfactory. Also the role of allogeneic stem cell transplantation is still unclear, although the few cases reported on the literature would seem to show good results in overall survival rates. In this paper, we reported the patient׳s medical history affected by a αβ variant of hepatosplenic T cell successfully rescued with a haploidentical transplant. Elsevier 2014-10-28 /pmc/articles/PMC4242978/ /pubmed/25429355 http://dx.doi.org/10.1016/j.lrr.2014.09.001 Text en © 2014 The Authors http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/).
spellingShingle Case Report
Catania, Gioacchino
Zallio, Francesco
Monaco, Federico
Corsetti, Maria Teresa
Trincheri, Nicol
Bonello, Lisa
Mele, Lia
Dallavalle, Franco
Salvi, Flavia
Pini, Massimo
Successful HLA haploidentical myeloablative stem cell transplantation for aggressive hepatosplenic alpha/beta (αβ) T-cell lymphoma
title Successful HLA haploidentical myeloablative stem cell transplantation for aggressive hepatosplenic alpha/beta (αβ) T-cell lymphoma
title_full Successful HLA haploidentical myeloablative stem cell transplantation for aggressive hepatosplenic alpha/beta (αβ) T-cell lymphoma
title_fullStr Successful HLA haploidentical myeloablative stem cell transplantation for aggressive hepatosplenic alpha/beta (αβ) T-cell lymphoma
title_full_unstemmed Successful HLA haploidentical myeloablative stem cell transplantation for aggressive hepatosplenic alpha/beta (αβ) T-cell lymphoma
title_short Successful HLA haploidentical myeloablative stem cell transplantation for aggressive hepatosplenic alpha/beta (αβ) T-cell lymphoma
title_sort successful hla haploidentical myeloablative stem cell transplantation for aggressive hepatosplenic alpha/beta (αβ) t-cell lymphoma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4242978/
https://www.ncbi.nlm.nih.gov/pubmed/25429355
http://dx.doi.org/10.1016/j.lrr.2014.09.001
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