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Modelling the onset of senescence at the G1/S cell cycle checkpoint

BACKGROUND: DNA damage (single or double-strand breaks) triggers adapted cellular responses. These responses are elicited through signalling pathways, which activate cell cycle checkpoints and basically lead to three cellular fates: cycle arrest promoting DNA repair, senescence (permanent arrest) or...

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Detalles Bibliográficos
Autores principales:	Mombach, José CM, Bugs, Cristhian A, Chaouiya, Claudine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243082/ https://www.ncbi.nlm.nih.gov/pubmed/25573782 http://dx.doi.org/10.1186/1471-2164-15-S7-S7

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