Structures of bacterial kynurenine formamidase reveal a crowded binuclear zinc catalytic site primed to generate a potent nucleophile

Tryptophan is an important precursor for chemical entities that ultimately support the biosynthesis of key metabolites. The second stage of tryptophan catabolism is catalysed by kynurenine formamidase, an enzyme that is different between eukaryotes and prokaryotes. In the present study, we character...

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Detalles Bibliográficos
Autores principales: Díaz-Sáez, Laura, Srikannathasan, Velupillai, Zoltner, Martin, Hunter, William N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243253/
https://www.ncbi.nlm.nih.gov/pubmed/24942958
http://dx.doi.org/10.1042/BJ20140511

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243253/
https://www.ncbi.nlm.nih.gov/pubmed/24942958
http://dx.doi.org/10.1042/BJ20140511

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