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Phytochemical and Pharmacological Investigation of Ethanol Extract of Cissampelos pareira
In this study, the ethanol extract of Cissampelos pareira has been evaluated. The extract was tested for analgesic properties using both hot plate and acetic acid-induced writhing methods. Antiinflammatory effect was investigated using two different doses of 250 and 500 mg/kg body weight on Evans ra...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243265/ https://www.ncbi.nlm.nih.gov/pubmed/25425762 |
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author | Reza, H. M. Shohel, M. Aziz, Sadia B. Pinaz, Farzana I. Uddin, M. F. Al-Amin, M Khan, I. N. Jain, Preeti |
author_facet | Reza, H. M. Shohel, M. Aziz, Sadia B. Pinaz, Farzana I. Uddin, M. F. Al-Amin, M Khan, I. N. Jain, Preeti |
author_sort | Reza, H. M. |
collection | PubMed |
description | In this study, the ethanol extract of Cissampelos pareira has been evaluated. The extract was tested for analgesic properties using both hot plate and acetic acid-induced writhing methods. Antiinflammatory effect was investigated using two different doses of 250 and 500 mg/kg body weight on Evans rats by carrageenan-induced paw edema test. The antipyretic activity was evaluated using Brewer's yeast-induced pyrexia in Wistar rats. The phytochemical screening of the extract of Cissampelos pareira exhibited the presence of several phytochemical compounds including saponins, gums and carbohydrates, reducing sugars, alkaloids and terpenoids. Ethanol extract of Cissampelos pareira exhibited significant analgesic, antiinflammatory and antipyretic activity in a dose-dependent manner. The results obtained from these studies confirm its therapeutic value against diseases caused by various pain and fever. |
format | Online Article Text |
id | pubmed-4243265 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-42432652014-11-25 Phytochemical and Pharmacological Investigation of Ethanol Extract of Cissampelos pareira Reza, H. M. Shohel, M. Aziz, Sadia B. Pinaz, Farzana I. Uddin, M. F. Al-Amin, M Khan, I. N. Jain, Preeti Indian J Pharm Sci Short Communication In this study, the ethanol extract of Cissampelos pareira has been evaluated. The extract was tested for analgesic properties using both hot plate and acetic acid-induced writhing methods. Antiinflammatory effect was investigated using two different doses of 250 and 500 mg/kg body weight on Evans rats by carrageenan-induced paw edema test. The antipyretic activity was evaluated using Brewer's yeast-induced pyrexia in Wistar rats. The phytochemical screening of the extract of Cissampelos pareira exhibited the presence of several phytochemical compounds including saponins, gums and carbohydrates, reducing sugars, alkaloids and terpenoids. Ethanol extract of Cissampelos pareira exhibited significant analgesic, antiinflammatory and antipyretic activity in a dose-dependent manner. The results obtained from these studies confirm its therapeutic value against diseases caused by various pain and fever. Medknow Publications & Media Pvt Ltd 2014 /pmc/articles/PMC4243265/ /pubmed/25425762 Text en Copyright: © Indian Journal of Pharmaceutical Sciences http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Short Communication Reza, H. M. Shohel, M. Aziz, Sadia B. Pinaz, Farzana I. Uddin, M. F. Al-Amin, M Khan, I. N. Jain, Preeti Phytochemical and Pharmacological Investigation of Ethanol Extract of Cissampelos pareira |
title | Phytochemical and Pharmacological Investigation of Ethanol Extract of Cissampelos pareira |
title_full | Phytochemical and Pharmacological Investigation of Ethanol Extract of Cissampelos pareira |
title_fullStr | Phytochemical and Pharmacological Investigation of Ethanol Extract of Cissampelos pareira |
title_full_unstemmed | Phytochemical and Pharmacological Investigation of Ethanol Extract of Cissampelos pareira |
title_short | Phytochemical and Pharmacological Investigation of Ethanol Extract of Cissampelos pareira |
title_sort | phytochemical and pharmacological investigation of ethanol extract of cissampelos pareira |
topic | Short Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243265/ https://www.ncbi.nlm.nih.gov/pubmed/25425762 |
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