The pathological effects of CCR2+ inflammatory monocytes are amplified by an IFNAR1-triggered chemokine feedback loop in highly pathogenic influenza infection

BACKGROUND: Highly pathogenic influenza viruses cause high levels of morbidity, including excessive infiltration of leukocytes into the lungs, high viral loads and a cytokine storm. However, the details of how these pathological features unfold in severe influenza infections remain unclear. Accumula...

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Detalles Bibliográficos
Autores principales: Lin, Sue-Jane, Lo, Ming, Kuo, Rei-Lin, Shih, Shin-Ru, Ojcius, David M, Lu, Jean, Lee, Chien-Kuo, Chen, Hui-Chen, Lin, Meei Yun, Leu, Chuen-Miin, Lin, Chia-Ni, Tsai, Ching-Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243311/
https://www.ncbi.nlm.nih.gov/pubmed/25407417
http://dx.doi.org/10.1186/s12929-014-0099-6

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