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Epidural administration of neostigmine-loaded nanofibers provides extended analgesia in rats

BACKGROUND: In this study, neostigmine-loaded electrospun nanofibers were prepared and then their efficacy and duration of analgesic action were studied after epidural administration in rats by repeated tail flick and formalin tests. METHODS: The neostigmine poly vinyl alcohol (PVA) nanofibers were...

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Detalles Bibliográficos
Autores principales: Yosefifard, Masoomeh, Hassanpour-Ezatti, Majid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243326/
https://www.ncbi.nlm.nih.gov/pubmed/25403313
http://dx.doi.org/10.1186/s40199-014-0073-6