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Inter-individual methylation variability in differentially methylated regions between maternal whole blood and first trimester CVS
BACKGROUND: DNA methylation is the most studied form of epigenetic regulation, a process by which chromatin composition and transcription factor binding is altered to influence tissue specific gene expression and differentiation. Such tissue specific methylation patterns are investigated as biomarke...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243368/ https://www.ncbi.nlm.nih.gov/pubmed/25426166 http://dx.doi.org/10.1186/s13039-014-0073-8 |