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A gene therapy induced emphysema model and the protective role of stem cells

BACKGROUND: Chronic obstructive pulmonary disease presents with two different phenotypes: chronic bronchitis and emphysema with parenchymal destruction. Decreased expression of vascular endothelial growth factor and increased endothelial cell apoptosis are considered major factors for emphysema. Ste...

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Detalles Bibliográficos
Autores principales: Zarogoulidis, Paul, Hohenforst-Schmidt, Wolfgang, Huang, Haidong, Sahpatzidou, Despoina, Freitag, Lutz, Sakkas, Leonidas, Rapti, Aggeliki, Kioumis, Ioannis, Pitsiou, Georgia, Kouzi-Koliakos, Kokkona, Papamichail, Anna, Papaiwannou, Antonis, Tsiouda, Theodora, Tsakiridis, Kosmas, Porpodis, Konstantinos, Lampaki, Sofia, Organtzis, John, Gschwendtner, Andreas, Zarogoulidis, Konstantinos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243373/
https://www.ncbi.nlm.nih.gov/pubmed/25394479
http://dx.doi.org/10.1186/s13000-014-0195-7