Ubiquitination as an Efficient Molecular Strategy Employed in Salmonella Infection

The ubiquitin modification has various functions in the host innate immune system in response to the bacterial infection. To counteract the host immunity, Salmonella can specifically target ubiquitin pathways by its effector proteins. In this review, we describe the multiple facets of ubiquitin func...

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Autores principales: Narayanan, Lakshmi A., Edelmann, Mariola J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243690/
https://www.ncbi.nlm.nih.gov/pubmed/25505465
http://dx.doi.org/10.3389/fimmu.2014.00558
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author Narayanan, Lakshmi A.
Edelmann, Mariola J.
author_facet Narayanan, Lakshmi A.
Edelmann, Mariola J.
author_sort Narayanan, Lakshmi A.
collection PubMed
description The ubiquitin modification has various functions in the host innate immune system in response to the bacterial infection. To counteract the host immunity, Salmonella can specifically target ubiquitin pathways by its effector proteins. In this review, we describe the multiple facets of ubiquitin function during infection with Salmonella enterica Typhimurium and hypothesize how these studies on the host–pathogen interactions can help to understand the general function of the ubiquitination pathway in the host cell.
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spelling pubmed-42436902014-12-10 Ubiquitination as an Efficient Molecular Strategy Employed in Salmonella Infection Narayanan, Lakshmi A. Edelmann, Mariola J. Front Immunol Immunology The ubiquitin modification has various functions in the host innate immune system in response to the bacterial infection. To counteract the host immunity, Salmonella can specifically target ubiquitin pathways by its effector proteins. In this review, we describe the multiple facets of ubiquitin function during infection with Salmonella enterica Typhimurium and hypothesize how these studies on the host–pathogen interactions can help to understand the general function of the ubiquitination pathway in the host cell. Frontiers Media S.A. 2014-11-25 /pmc/articles/PMC4243690/ /pubmed/25505465 http://dx.doi.org/10.3389/fimmu.2014.00558 Text en Copyright © 2014 Narayanan and Edelmann. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Immunology
Narayanan, Lakshmi A.
Edelmann, Mariola J.
Ubiquitination as an Efficient Molecular Strategy Employed in Salmonella Infection
title Ubiquitination as an Efficient Molecular Strategy Employed in Salmonella Infection
title_full Ubiquitination as an Efficient Molecular Strategy Employed in Salmonella Infection
title_fullStr Ubiquitination as an Efficient Molecular Strategy Employed in Salmonella Infection
title_full_unstemmed Ubiquitination as an Efficient Molecular Strategy Employed in Salmonella Infection
title_short Ubiquitination as an Efficient Molecular Strategy Employed in Salmonella Infection
title_sort ubiquitination as an efficient molecular strategy employed in salmonella infection
topic Immunology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243690/
https://www.ncbi.nlm.nih.gov/pubmed/25505465
http://dx.doi.org/10.3389/fimmu.2014.00558
work_keys_str_mv AT narayananlakshmia ubiquitinationasanefficientmolecularstrategyemployedinsalmonellainfection
AT edelmannmariolaj ubiquitinationasanefficientmolecularstrategyemployedinsalmonellainfection

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