The Molecular Mechanism of Rhein in Diabetic Nephropathy

Diabetic nephropathy (DN) is characterized by unclear pathogenesis. Recent medical data shows that the incidence of DN rises year by year. Rhein is the main compositions of rhubarb, a traditional Chinese medicinal plant, which plays an active role in kidney protection. The prophylaxis and phytothera...

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Autores principales: Zeng, Cong-Cong, Liu, Xi, Chen, Guo-Rong, Wu, Qian-Jia, Liu, Wang-Wang, Luo, Hai-Ying, Cheng, Jin-Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243766/
https://www.ncbi.nlm.nih.gov/pubmed/25435889
http://dx.doi.org/10.1155/2014/487097
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author Zeng, Cong-Cong
Liu, Xi
Chen, Guo-Rong
Wu, Qian-Jia
Liu, Wang-Wang
Luo, Hai-Ying
Cheng, Jin-Guo
author_facet Zeng, Cong-Cong
Liu, Xi
Chen, Guo-Rong
Wu, Qian-Jia
Liu, Wang-Wang
Luo, Hai-Ying
Cheng, Jin-Guo
author_sort Zeng, Cong-Cong
collection PubMed
description Diabetic nephropathy (DN) is characterized by unclear pathogenesis. Recent medical data shows that the incidence of DN rises year by year. Rhein is the main compositions of rhubarb, a traditional Chinese medicinal plant, which plays an active role in kidney protection. The prophylaxis and phytotherapeutic effects of rhein are due to its anti-inflammatory and antifibrosis properties. Here, we shed light on the renal protective role of rhein in diabetes mellitus (DM) with a particular focus on the molecular basis of this effect.
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spelling pubmed-42437662014-11-30 The Molecular Mechanism of Rhein in Diabetic Nephropathy Zeng, Cong-Cong Liu, Xi Chen, Guo-Rong Wu, Qian-Jia Liu, Wang-Wang Luo, Hai-Ying Cheng, Jin-Guo Evid Based Complement Alternat Med Review Article Diabetic nephropathy (DN) is characterized by unclear pathogenesis. Recent medical data shows that the incidence of DN rises year by year. Rhein is the main compositions of rhubarb, a traditional Chinese medicinal plant, which plays an active role in kidney protection. The prophylaxis and phytotherapeutic effects of rhein are due to its anti-inflammatory and antifibrosis properties. Here, we shed light on the renal protective role of rhein in diabetes mellitus (DM) with a particular focus on the molecular basis of this effect. Hindawi Publishing Corporation 2014 2014-11-11 /pmc/articles/PMC4243766/ /pubmed/25435889 http://dx.doi.org/10.1155/2014/487097 Text en Copyright © 2014 Cong-Cong Zeng et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Zeng, Cong-Cong
Liu, Xi
Chen, Guo-Rong
Wu, Qian-Jia
Liu, Wang-Wang
Luo, Hai-Ying
Cheng, Jin-Guo
The Molecular Mechanism of Rhein in Diabetic Nephropathy
title The Molecular Mechanism of Rhein in Diabetic Nephropathy
title_full The Molecular Mechanism of Rhein in Diabetic Nephropathy
title_fullStr The Molecular Mechanism of Rhein in Diabetic Nephropathy
title_full_unstemmed The Molecular Mechanism of Rhein in Diabetic Nephropathy
title_short The Molecular Mechanism of Rhein in Diabetic Nephropathy
title_sort molecular mechanism of rhein in diabetic nephropathy
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243766/
https://www.ncbi.nlm.nih.gov/pubmed/25435889
http://dx.doi.org/10.1155/2014/487097
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