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A point mutation in cpsE renders Streptococcus pneumoniae nonencapsulated and enhances its growth, adherence and competence

BACKGROUND: The polysaccharide capsule is a major virulence factor of the important human pathogen Streptococcus pneumoniae. However, S. pneumoniae strains lacking capsule do occur. RESULTS: Here, we report a nasopharyngeal isolate of Streptococcus pneumoniae composed of a mixture of two phenotypes;...

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Detalles Bibliográficos
Autores principales:	Schaffner, Thierry O, Hinds, Jason, Gould, Katherine A, Wüthrich, Daniel, Bruggmann, Rémy, Küffer, Marianne, Mühlemann, Kathrin, Hilty, Markus, Hathaway, Lucy J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243769/ https://www.ncbi.nlm.nih.gov/pubmed/25163487 http://dx.doi.org/10.1186/s12866-014-0210-x

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