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The Risk of Lung Cancer After Cessation of Asbestos Exposure in Construction Workers Using Pleural Malignant Mesothelioma as a Marker of Exposure

OBJECTIVE: To study the risk of lung cancer in heavily asbestos-exposed workers after the exposure to asbestos has ended. METHODS: Lung cancer was studied in a cohort of 189,896 Swedish construction workers through a linkage with the Swedish Cancer Registry. Asbestos exposure was estimated by the in...

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Detalles Bibliográficos
Autores principales: Järvholm, Bengt, Åström, Evelina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American College of Occupational and Environmental Medicine 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243788/
https://www.ncbi.nlm.nih.gov/pubmed/25479300
http://dx.doi.org/10.1097/JOM.0000000000000258
Descripción
Sumario:OBJECTIVE: To study the risk of lung cancer in heavily asbestos-exposed workers after the exposure to asbestos has ended. METHODS: Lung cancer was studied in a cohort of 189,896 Swedish construction workers through a linkage with the Swedish Cancer Registry. Asbestos exposure was estimated by the incidence of malignant mesothelioma in the occupational group. RESULTS: There were in total 2835 cases of lung cancer. Workers with heavy exposure to asbestos had an increased risk of lung cancer (relative risks = 1.74; 95% confidence interval, 1.25 to 2.41) before exposure ended and a similar risk to those with low exposure 20 years after the exposure had ceased (relative risks = 0.94; 95% confidence interval, 0.77 to 1.15). CONCLUSIONS: Workers with heavy exposure to asbestos have a similar risk of lung cancer as persons with low or no exposure 20 years after the exposure has ended.