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Capturing needles in haystacks: a comparison of B-cell receptor sequencing methods

BACKGROUND: Deep-sequencing methods are rapidly developing in the field of B-cell receptor (BCR) and T-cell receptor (TCR) diversity. These promise to revolutionise our understanding of adaptive immune dynamics, identify novel antibodies, and allow monitoring of minimal residual disease. However, di...

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Detalles Bibliográficos
Autores principales: Bashford-Rogers, Rachael JM, Palser, Anne L, Idris, Saad F, Carter, Lisa, Epstein, Michael, Callard, Robin E, Douek, Daniel C, Vassiliou, George S, Follows, George A, Hubank, Mike, Kellam, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243823/
https://www.ncbi.nlm.nih.gov/pubmed/25189176
http://dx.doi.org/10.1186/s12865-014-0029-0