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Complement factor C5a induces atherosclerotic plaque disruptions
Complement factor C5a and its receptor C5aR are expressed in vulnerable atherosclerotic plaques; however, a causal relation between C5a and plaque rupture has not been established yet. Accelerated atherosclerosis was induced by placing vein grafts in male apoE(−/−) mice. After 24 days, when advanced...
Autores principales: | Wezel, Anouk, de Vries, Margreet R, Lagraauw, H Maxime, Foks, Amanda C, Kuiper, Johan, Quax, Paul HA, Bot, Ilze |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244017/ https://www.ncbi.nlm.nih.gov/pubmed/25124749 http://dx.doi.org/10.1111/jcmm.12357 |
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