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Acute bronchodilator responses decline progressively over 4 years in patients with moderate to very severe COPD

BACKGROUND: We previously reported a progressive decline in absolute responses of FEV(1) and FVC to a near-maximal dose of 2 different short-acting bronchodilators over 4 years. Since varying host factors and the method of expressing the response may impact the time trend of acute bronchodilator res...

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Detalles Bibliográficos
Autores principales: Tashkin, Donald P, Li, Ning, Kleerup, Eric C, Halpin, David, Celli, Bartolome, Decramer, Marc, Elashoff, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244051/
https://www.ncbi.nlm.nih.gov/pubmed/25175805
http://dx.doi.org/10.1186/s12931-014-0102-5