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Acute bronchodilator responses decline progressively over 4 years in patients with moderate to very severe COPD
BACKGROUND: We previously reported a progressive decline in absolute responses of FEV(1) and FVC to a near-maximal dose of 2 different short-acting bronchodilators over 4 years. Since varying host factors and the method of expressing the response may impact the time trend of acute bronchodilator res...
Autores principales: | Tashkin, Donald P, Li, Ning, Kleerup, Eric C, Halpin, David, Celli, Bartolome, Decramer, Marc, Elashoff, Robert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244051/ https://www.ncbi.nlm.nih.gov/pubmed/25175805 http://dx.doi.org/10.1186/s12931-014-0102-5 |
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