Gentiolactone, a Secoiridoid Dilactone from Gentiana triflora, Inhibits TNF-α, iNOS and Cox-2 mRNA Expression and Blocks NF-κB Promoter Activity in Murine Macrophages

BACKGROUND: Gentian roots have been used as a herbal medicine because of their anti-inflammatory activities. However, the molecular mechanisms of these anti-inflammatory effects remain to be completely explained. METHODS AND FINDINGS: Here, we investigated anti-inflammatory effects of gentian roots...

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Detalles Bibliográficos
Autores principales: Yamada, Hidetoshi, Kikuchi, Sayaka, Inui, Tomoki, Takahashi, Hideyuki, Kimura, Ken-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244148/
https://www.ncbi.nlm.nih.gov/pubmed/25423092
http://dx.doi.org/10.1371/journal.pone.0113834

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244148/
https://www.ncbi.nlm.nih.gov/pubmed/25423092
http://dx.doi.org/10.1371/journal.pone.0113834

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