Constitutively Active FOXO1 Diminishes Activin Induction of Fshb Transcription in Immortalized Gonadotropes

In the present study, we investigate whether the FOXO1 transcription factor modulates activin signaling in pituitary gonadotropes. Our studies show that overexpression of constitutively active FOXO1 decreases activin induction of murine Fshb gene expression in immortalized LβT2 cells. We demonstrate...

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Detalles Bibliográficos
Autores principales: Park, Chung Hyun, Skarra, Danalea V., Rivera, Alissa J., Arriola, David J., Thackray, Varykina G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244159/
https://www.ncbi.nlm.nih.gov/pubmed/25423188
http://dx.doi.org/10.1371/journal.pone.0113839

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