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The Golgi S-acylation machinery comprises zDHHC enzymes with major differences in substrate affinity and S-acylation activity
S-acylation, the attachment of fatty acids onto cysteine residues, regulates protein trafficking and function and is mediated by a family of zDHHC enzymes. The S-acylation of peripheral membrane proteins has been proposed to occur at the Golgi, catalyzed by an S-acylation machinery that displays lit...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244197/ https://www.ncbi.nlm.nih.gov/pubmed/25253725 http://dx.doi.org/10.1091/mbc.E14-06-1169 |