Cargando…
Acute increase of α-synuclein inhibits synaptic vesicle recycling evoked during intense stimulation
Parkinson's disease is associated with multiplication of the α-synuclein gene and abnormal accumulation of the protein. In animal models, α-synuclein overexpression broadly impairs synaptic vesicle trafficking. However, the exact steps of the vesicle trafficking pathway affected by excess α-syn...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244201/ https://www.ncbi.nlm.nih.gov/pubmed/25273557 http://dx.doi.org/10.1091/mbc.E14-02-0708 |