Cargando…

Distribution, Molecular Structure and Functional Analysis of Carnitine Transporter (SLC22A5) in Canine Lens Epithelial Cells

While carnitine has been reported to have an anti-oxidative role on the ocular surface, there has been no report on the existence of a carnitine transporter (SLC22A5) in the lens. Therefore, we investigated the carnitine transport activity of canine lens epithelial cells (LEC) and determined the mol...

Descripción completa

Detalles Bibliográficos
Autores principales:	OCHIAI, Hideharu, KANEMAKI, Nobuyuki, SATO, Reiichiro, ONDA, Ken
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Japanese Association for Laboratory Animal Science 2014
Materias:	Original
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244295/ https://www.ncbi.nlm.nih.gov/pubmed/25048262 http://dx.doi.org/10.1538/expanim.63.467

Ejemplares similares

Analysis of Cationic Amino Acid Transport Activity in Canine Lens Epithelial Cells
por: Ochiai, Hideharu, et al.
Publicado: (2013)

Canine Amino Acid Transport System X(c)(–): cDNA Sequence, Distribution and Cystine Transport Activity in Lens Epithelial Cells
por: MARUO, Takuya, et al.
Publicado: (2013)

Analysis of L-type amino acid transporter in canine hepatocellular carcinoma
por: OGIHARA, Kikumi, et al.
Publicado: (2015)

Evidence of LAT1 expression in canine caput epididymis
por: OGIHARA, Kikumi, et al.
Publicado: (2014)

Aquaporin 1 expression in tissues of canines possessing inherited high K(+) erythrocytes
por: Ochiai, Hideharu, et al.
Publicado: (2008)

Characterization of Exosomal SLC22A5 (OCTN2) carnitine transporter
por: Console, Lara, et al.
Publicado: (2018)

Transrectal guidance of the ovaries reduces operative time during bovine laparoscopic ovariectomy
por: SATO, Reiichiro, et al.
Publicado: (2017)

SLC22A5 (OCTN2) Carnitine Transporter—Indispensable for Cell Metabolism, a Jekyll and Hyde of Human Cancer
por: Juraszek, Barbara, et al.
Publicado: (2019)

The Mitochondrial Carnitine Acyl-carnitine Carrier (SLC25A20): Molecular Mechanisms of Transport, Role in Redox Sensing and Interaction with Drugs
por: Tonazzi, Annamaria, et al.
Publicado: (2021)

Identification of SLC22A5 Gene Mutation in a Family with Carnitine Uptake Defect
por: Mutlu-Albayrak, Hatice, et al.
Publicado: (2015)

Broadening the Spectrum of SLC22A5 Phenotype: Primary Carnitine Deficiency Presenting with Focal Myoclonus
por: Khries, Maymunah, et al.
Publicado: (2023)

A nasal osteoma with an acute course in a Japanese Black heifer
por: SATO, Reiichiro, et al.
Publicado: (2017)

Maternal Primary Carnitine Deficiency and a Novel Solute Carrier Family 22 Member 5 (SLC22A5) Mutation
por: Jakoby, Michael, et al.
Publicado: (2021)

Transport of L-carnitine in human corneal and conjunctival epithelial cells
por: Xu, Shunjiang, et al.
Publicado: (2010)

Trospium Chloride Transport by Mouse Drug Carriers of the Slc22 and Slc47 Families
por: Gorecki, Matthias, et al.
Publicado: (2020)

Genetic Heterogeneity of SLC22 Family of Transporters in Drug Disposition
por: Lozano, Elisa, et al.
Publicado: (2018)

OCTN2-Mediated Acetyl-l-Carnitine Transport in Human Pulmonary Epithelial Cells In Vitro
por: Salomon, Johanna J., et al.
Publicado: (2019)

Congenital anterior staphyloma associated with Peters’ anomaly and aphakia in a Holstein calf
por: SATO, Reiichiro, et al.
Publicado: (2017)

Uptake Transporters of the SLC21, SLC22A, and SLC15A Families in Anticancer Therapy—Modulators of Cellular Entry or Pharmacokinetics?
por: Brecht, Karin, et al.
Publicado: (2020)

Interaction of Natural Dietary and Herbal Anionic Compounds and Flavonoids with Human Organic Anion Transporters 1 (SLC22A6), 3 (SLC22A8), and 4 (SLC22A11)
por: Wang, Li, et al.
Publicado: (2013)

In Silico Analysis of the Structural Dynamics and Substrate Recognition Determinants of the Human Mitochondrial Carnitine/Acylcarnitine SLC25A20 Transporter
por: Pasquadibisceglie, Andrea, et al.
Publicado: (2023)

Organic Anion Transporters (OAT) and Other SLC22 Transporters in Progression of Renal Cell Carcinoma
por: Whisenant, Thomas C., et al.
Publicado: (2022)

Metabolic Flexibility in Canine Mammary Tumors: Implications of the Carnitine System
por: Cacciola, Nunzio Antonio, et al.
Publicado: (2021)

A mutation creating an upstream translation initiation codon in SLC22A5 5′UTR is a frequent cause of primary carnitine deficiency
por: Ferdinandusse, Sacha, et al.
Publicado: (2019)

Downregulation of organic cation transporters OCT1 (SLC22A1) and OCT3 (SLC22A3) in human hepatocellular carcinoma and their prognostic significance
por: Heise, Michael, et al.
Publicado: (2012)

Genetic and Epigenetic Regulation of the Organic Cation Transporter 3, SLC22A3
por: Chen, Ligong, et al.
Publicado: (2012)

Introduction of Organic Anion Transporters (SLC22A) and a Regulatory Mechanism by Caveolins
por: Lee, Woon Kyu, et al.
Publicado: (2006)

Interactions of antiretroviral drugs with the SLC22A1 (OCT1) drug transporter
por: Moss, Darren M., et al.
Publicado: (2015)

Effect of Cholesterol on the Organic Cation Transporter OCTN1 (SLC22A4)
por: Pochini, Lorena, et al.
Publicado: (2020)

SLC22 Transporters in the Fly Renal System Regulate Response to Oxidative Stress In Vivo
por: Zhang, Patrick, et al.
Publicado: (2021)

Illuminating the Function of the Orphan Transporter, SLC22A10 in Humans and Other Primates
por: Yee, Sook Wah, et al.
Publicado: (2023)

Illuminating the Function of the Orphan Transporter, SLC22A10 in Humans and Other Primates
por: Yee, Sook Wah, et al.
Publicado: (2023)

Residual OCTN2 transporter activity, carnitine levels and symptoms correlate in patients with primary carnitine deficiency
por: Rasmussen, Jan, et al.
Publicado: (2014)

ERα increases expression and interacts with TERT in cataractous canine lens epithelial cells
por: Colitz, Carmen M.H., et al.
Publicado: (2009)

Metformin Pharmacogenetics: Effects of SLC22A1, SLC22A2, and SLC22A3 Polymorphisms on Glycemic Control and HbA1c Levels
por: AL-Eitan, Laith N., et al.
Publicado: (2019)

Active Hydrophilic Components of the Medicinal Herb Salvia miltiorrhiza (Danshen) Potently Inhibit Organic Anion Transporters 1 (Slc22a6) and 3 (Slc22a8)
por: Wang, Li, et al.
Publicado: (2012)

Interactions of 172 plant extracts with human organic anion transporter 1 (SLC22A6) and 3 (SLC22A8): a study on herb-drug interactions
por: Lu, Hang, et al.
Publicado: (2017)

Functional Characterization of Rare Variants in OAT1/SLC22A6 and OAT3/SLC22A8 Urate Transporters Identified in a Gout and Hyperuricemia Cohort
por: Vávra, Jiří, et al.
Publicado: (2022)

The influence of metformin transporter gene SLC22A1 and SLC47A1 variants on steady-state pharmacokinetics and glycemic response
por: Ningrum, Vitarani Dwi Ananda, et al.
Publicado: (2022)

Identification and characterization of a carnitine transporter in Acinetobacter baumannii
por: Breisch, Jennifer, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_nbhru7p2dh3anfvhef23gk79mt