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Regulation of miRNA-mediated gene silencing by miRNA precursors
Processing of miRNAs from their precursors to the biologically active mature form is regulated during development and cancer. We show that mouse precursor-miR-151 can bind to and compete with mature miR-151-5p and miR-151-3p for binding sites contained within the complementary regions of the E2f6 mR...
Autores principales: | Roy-Chaudhuri, Biswajoy, Valdmanis, Paul N., Zhang, Yue, Wang, Qing, Luo, Qingjun, Kay, Mark A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244528/ https://www.ncbi.nlm.nih.gov/pubmed/25086740 http://dx.doi.org/10.1038/nsmb.2862 |
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