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Development of Small Molecular Proteasome Inhibitors Using a Caenorhabditis elegans Screen
We have developed a screening protocol to identify compounds with characteristics of small molecule proteasome inhibitors using the real-time analysis of the Caenorhabditis elegans germ line. This screen is able to identify compounds that induce germ line phenotypes characteristic of a reduction in...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244688/ https://www.ncbi.nlm.nih.gov/pubmed/25436151 http://dx.doi.org/10.1155/2014/237286 |