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Donor and tissue profile of a community eye bank in Eastern India

PURPOSE: The purpose of this study is to analyze the donor and tissue profile of a community eye bank in Eastern India. MATERIALS AND METHODS: Eye bank records were analyzed for the period July 2007-June 2011. Variables analyzed included donor demographics (age, gender, and ethnicity), donor cause o...

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Detalles Bibliográficos
Autores principales: Ranjan, Abhishek, Das, Sujata, Sahu, Srikant K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244740/
https://www.ncbi.nlm.nih.gov/pubmed/25370396
http://dx.doi.org/10.4103/0301-4738.138298
Descripción
Sumario:PURPOSE: The purpose of this study is to analyze the donor and tissue profile of a community eye bank in Eastern India. MATERIALS AND METHODS: Eye bank records were analyzed for the period July 2007-June 2011. Variables analyzed included donor demographics (age, gender, and ethnicity), donor cause of death, consent for recovery, death-to-preservation interval, preservation-to-utilization interval, endothelial cell density (ECD), corneal suitability for transplantation, and corneal tissue utilization. RESULTS: During this study period, 743 corneal tissues were retrieved from 373 donors (male:female = 263:110). The mean age of donors was 52 ± 21 years (range: 3-95 years). The most common donor age group was 41-50 and 71-80 years. Most of the donors belonged to one religious faith (99%). The most common causes of death were cardiorespiratory failure (34%) followed by road traffic accident (30%). Majority donors were motivated (n = 320; 86%), and remaining (n = 53; 14%) were voluntary. Most of the consents were given by sons or daughters of the deceased (45%) followed by siblings (18%). Mean death-to-preservation interval was 3.9 ± 1.9 h. Mean preservation-to-utilization interval was 56.0 ± 24.4 h. The mean ECD of donor corneal tissue was 2857 ± 551 cells/mm(2) and the median value was 2898 cells/mm(2). Of harvested corneas 556 (75%) corneal tissues were utilized. The most common causes of nonutilization were septicemia in donor (n = 56; 30%) and poor quality of tissue (n = 55; 30%). CONCLUSIONS: Although, there is significant corneal tissue utilization, there is a need for increased awareness among people in order to augment voluntary donations.