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Brachytherapy, A viable option of globe salvage in treatment of large ciliary body melanocytoma

We report a case of large histopathologically proven melanocytoma of the ciliary body in a 15-year-old male, presented with rapid extraocular growth following incisional biopsy with scleral patch graft. We chose brachytherapy with Ruthenium 106 plaque over enucleation as the later was refused by the...

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Autores principales: Shanmugam, Mahesh P., Saxena, Manish, Ramanjulu, Rajesh, Tekwani, Pradeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244750/
https://www.ncbi.nlm.nih.gov/pubmed/25370406
http://dx.doi.org/10.4103/0301-4738.143953
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author Shanmugam, Mahesh P.
Saxena, Manish
Ramanjulu, Rajesh
Tekwani, Pradeep
author_facet Shanmugam, Mahesh P.
Saxena, Manish
Ramanjulu, Rajesh
Tekwani, Pradeep
author_sort Shanmugam, Mahesh P.
collection PubMed
description We report a case of large histopathologically proven melanocytoma of the ciliary body in a 15-year-old male, presented with rapid extraocular growth following incisional biopsy with scleral patch graft. We chose brachytherapy with Ruthenium 106 plaque over enucleation as the later was refused by the parents. The initial apical height of the tumor was 14.2 mm on ultrasonography. Two weeks after brachytherapy, the mass regressed to a size of 8.1 mm and 1 year later to 6.7 mm. This is the first case report showing the response of brachytherapy to ciliary body melanocytoma, which results in ocular and visual acuity salvation with considerable decreased in size of the tumor. The authors conclude that brachytherapy is an option in the management of non-resectable melanocytoma of the ciliary body.
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spelling pubmed-42447502014-12-01 Brachytherapy, A viable option of globe salvage in treatment of large ciliary body melanocytoma Shanmugam, Mahesh P. Saxena, Manish Ramanjulu, Rajesh Tekwani, Pradeep Indian J Ophthalmol Brief Communications We report a case of large histopathologically proven melanocytoma of the ciliary body in a 15-year-old male, presented with rapid extraocular growth following incisional biopsy with scleral patch graft. We chose brachytherapy with Ruthenium 106 plaque over enucleation as the later was refused by the parents. The initial apical height of the tumor was 14.2 mm on ultrasonography. Two weeks after brachytherapy, the mass regressed to a size of 8.1 mm and 1 year later to 6.7 mm. This is the first case report showing the response of brachytherapy to ciliary body melanocytoma, which results in ocular and visual acuity salvation with considerable decreased in size of the tumor. The authors conclude that brachytherapy is an option in the management of non-resectable melanocytoma of the ciliary body. Medknow Publications & Media Pvt Ltd 2014-09 /pmc/articles/PMC4244750/ /pubmed/25370406 http://dx.doi.org/10.4103/0301-4738.143953 Text en Copyright: © Indian Journal of Ophthalmology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Brief Communications
Shanmugam, Mahesh P.
Saxena, Manish
Ramanjulu, Rajesh
Tekwani, Pradeep
Brachytherapy, A viable option of globe salvage in treatment of large ciliary body melanocytoma
title Brachytherapy, A viable option of globe salvage in treatment of large ciliary body melanocytoma
title_full Brachytherapy, A viable option of globe salvage in treatment of large ciliary body melanocytoma
title_fullStr Brachytherapy, A viable option of globe salvage in treatment of large ciliary body melanocytoma
title_full_unstemmed Brachytherapy, A viable option of globe salvage in treatment of large ciliary body melanocytoma
title_short Brachytherapy, A viable option of globe salvage in treatment of large ciliary body melanocytoma
title_sort brachytherapy, a viable option of globe salvage in treatment of large ciliary body melanocytoma
topic Brief Communications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244750/
https://www.ncbi.nlm.nih.gov/pubmed/25370406
http://dx.doi.org/10.4103/0301-4738.143953
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