Cargando…
Synthesis and Biological Evaluation of QRSTUVWXYZA′ Domains of Maitotoxin
[Image: see text] The synthesis of QRSTUVWXYZA′ domains 7, 8, and 9 of the highly potent marine neurotoxin maitotoxin (1), the largest secondary metabolite isolated to date, is described. The devised synthetic strategy entailed a cascade Takai–Utimoto ester olefination/ring closing metathesis to con...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2014
|
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244842/ https://www.ncbi.nlm.nih.gov/pubmed/25374117 http://dx.doi.org/10.1021/ja509829e |