Cargando…

Roles of 5-Lipoxygenase and Cysteinyl-Leukotriene Type 1 Receptors in the Hematological Response to Allergen Challenge and Its Prevention by Diethylcarbamazine in a Murine Model of Asthma

Diethylcarbamazine (DEC), which blocks leukotriene production, abolishes the challenge-induced increase in eosinopoiesis in bone-marrow from ovalbumin- (OVA-) sensitized mice, suggesting that 5-lipoxygenase (5-LO) products contribute to the hematological responses in experimental asthma models. We e...

Descripción completa

Detalles Bibliográficos
Autores principales:	Masid-de-Brito, Daniela, Queto, Túlio, Gaspar-Elsas, Maria Ignez C., Xavier-Elsas, Pedro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244945/ https://www.ncbi.nlm.nih.gov/pubmed/25477712 http://dx.doi.org/10.1155/2014/403970

Ejemplares similares

Odd couple: The unexpected partnership of glucocorticoid hormones and cysteinyl-leukotrienes in the extrinsic regulation of murine bone-marrow eosinopoiesis
por: Xavier-Elsas, Pedro, et al.
Publicado: (2017)

5-Lipoxygenase-Dependent Recruitment of Neutrophils and Macrophages by Eotaxin-Stimulated Murine Eosinophils
por: Luz, Ricardo Alves, et al.
Publicado: (2014)

Blockage of Eosinopoiesis by IL-17A Is Prevented by Cytokine and Lipid Mediators of Allergic Inflammation
por: Xavier-Elsas, Pedro, et al.
Publicado: (2015)

The In Vivo Granulopoietic Response to Dexamethasone Injection Is Abolished in Perforin-Deficient Mutant Mice and Corrected by Lymphocyte Transfer from Nonsensitized Wild-Type Donors
por: Xavier-Elsas, Pedro, et al.
Publicado: (2015)

Adipokines and Cysteinyl Leukotrienes in the Pathogenesis of Asthma
por: Coffey, Michael J., et al.
Publicado: (2015)

Surgical and immune reconstitution murine models in bone marrow research: Potential for exploring mechanisms in sepsis, trauma and allergy
por: Xavier-Elsas, Pedro, et al.
Publicado: (2017)

Essential Roles of PKA, iNOS, CD95/CD95L, and Terminal Caspases in Suppression of Eosinopoiesis by PGE2 and Other cAMP-Elevating Agents
por: de Luca, Bianca, et al.
Publicado: (2013)

Cysteinyl Leukotriene Pathway and Cancer
por: Tsai, Ming-Ju, et al.
Publicado: (2021)

Cysteinyl Leukotriene Receptor Antagonists Decrease Cancer Risk in Asthma Patients
por: Tsai, Ming-Ju, et al.
Publicado: (2016)

Cysteinyl Leukotrienes and Their Receptors; Emerging Concepts
por: Kanaoka, Yoshihide, et al.
Publicado: (2014)

Cysteinyl-Leukotriene Receptors and Cellular Signals
por: Rovati, G. Enrico, et al.
Publicado: (2007)

Involvement of 5-lipoxygenase/cysteinyl leukotriene receptor 1 in rotenone- and MPP+-induced BV2 microglial activation
por: Wang, Yanfang, et al.
Publicado: (2012)

Cysteinyl-leukotrienes in the regulation of β(2)-adrenoceptor function: an in vitro model of asthma
por: Rovati, G Enrico, et al.
Publicado: (2006)

Corrigendum: Cysteinyl Leukotriene Receptor Antagonists Decrease Cancer Risk in Asthma Patients
por: Tsai, Ming-Ju, et al.
Publicado: (2016)

Cysteinyl-leukotrienes promote cutaneous Leishmaniasis control
por: Noronha, Letícia Paula Trajano, et al.
Publicado: (2023)

Cysteinyl Leukotriene and Systemic Inflammatory Levels in Preeclampsia
por: Guzeltas, Gokhan, et al.
Publicado: (2023)

Modulation of the Effects of Lung Immune Response on Bone Marrow by Oral Antigen Exposure
por: Xavier-Elsas, P., et al.
Publicado: (2013)

Cysteinyl leukotrienes: multi-functional mediators in allergic rhinitis
por: Peters-Golden, M, et al.
Publicado: (2006)

Cysteinyl Leukotrienes as Potential Pharmacological Targets for Cerebral Diseases
por: Gelosa, Paolo, et al.
Publicado: (2017)

Role of the Cysteinyl Leukotrienes in the Pathogenesis and Progression of Cardiovascular Diseases
por: Colazzo, Francesca, et al.
Publicado: (2017)

Transforming growth factor β1-induced astrocyte migration is mediated in part by activating 5-lipoxygenase and cysteinyl leukotriene receptor 1
por: Huang, Xue-Qin, et al.
Publicado: (2012)

Exhaled breath condensate cysteinyl leukotrienes and airway remodeling in childhood asthma: a pilot study
por: Lex, Christiane, et al.
Publicado: (2006)

Montelukast: More than a Cysteinyl Leukotriene Receptor Antagonist?
por: Tintinger, Gregory R., et al.
Publicado: (2010)

Characterisation of P2Y(12) Receptor Responsiveness to Cysteinyl Leukotrienes
por: Foster, Holly R., et al.
Publicado: (2013)

Multifaceted Roles of Cysteinyl Leukotrienes in Eliciting Eosinophil Granule Protein Secretion
por: Baptista-dos-Reis, Renata, et al.
Publicado: (2015)

Evaluation of Cysteinyl Leukotriene Signaling as a Therapeutic Target for Colorectal Cancer
por: Burke, Lorraine, et al.
Publicado: (2016)

Small-wedge synchrotron and serial XFEL datasets for Cysteinyl leukotriene GPCRs
por: Marin, Egor, et al.
Publicado: (2020)

Structural basis of ligand selectivity and disease mutations in cysteinyl leukotriene receptors
por: Gusach, Anastasiia, et al.
Publicado: (2019)

Structure-based mechanism of cysteinyl leukotriene receptor inhibition by antiasthmatic drugs
por: Luginina, Aleksandra, et al.
Publicado: (2019)

Cysteinyl leukotriene receptor 1 is dispensable for osteoclast differentiation and bone resorption
por: Fujita, Hirofumi, et al.
Publicado: (2022)

5-Lipoxygenase and cysteinyl leukotriene receptor 1 regulate epidermal growth factor-induced cell migration through Tiam1 upregulation and Rac1 activation
por: Magi, Shigeyuki, et al.
Publicado: (2014)

Interleukin-13, but Not Indomethacin, Increases Cysteinyl-Leukotriene Synthesis in Human Lung Macrophages
por: Jackson, Sarah E., et al.
Publicado: (2012)

Dectin-2 mediates Th2 immunity through the generation of cysteinyl leukotrienes
por: Barrett, Nora A., et al.
Publicado: (2011)

Cysteinyl Leukotriene Signaling Aggravates Myocardial Hypoxia in Experimental Atherosclerotic Heart Disease
por: Nobili, Elena, et al.
Publicado: (2012)

Cysteinyl Leukotriene Receptor-1 Antagonists as Modulators of Innate Immune Cell Function
por: Theron, A. J., et al.
Publicado: (2014)

Cysteinyl leukotriene receptor 1 antagonism prevents experimental abdominal aortic aneurysm
por: Di Gennaro, Antonio, et al.
Publicado: (2018)

Cysteinyl Leukotrienes in Eosinophil Biology: Functional Roles and Therapeutic Perspectives in Eosinophilic Disorders
por: Thompson-Souza, Glaucia A., et al.
Publicado: (2017)

Chlorine Gas, Airway Inflammation, and Cysteinyl Leukotrienes: The Neutrophil Does Not Work Alone
por: Sporn, Peter H. S.
Publicado: (2020)

Cysteinyl–leukotriene and prostaglandin pathways in bronchial versus alveolar lavage in allergic asthmatics
por: van der Burg, Nicole, et al.
Publicado: (2022)

Leukotriene E(4) is a full functional agonist for human cysteinyl leukotriene type 1 receptor-dependent gene expression
por: Foster, Holly R., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_q1t489gsff2v12qtm9vl4vnrn5