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Role of the Prostaglandin E(2) EP1 Receptor in Traumatic Brain Injury
Brain injuries promote upregulation of so-called proinflammatory prostaglandins, notably prostaglandin E(2) (PGE(2)), leading to overactivation of a class of its cognate G-protein-coupled receptors, including EP1, which is considered a promising target for treatment of ischemic stroke. However, the...
Autores principales: | Glushakov, Alexander V., Fazal, Jawad A., Narumiya, Shuh, Doré, Sylvain |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245217/ https://www.ncbi.nlm.nih.gov/pubmed/25426930 http://dx.doi.org/10.1371/journal.pone.0113689 |
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