Novel Orally Swallowable IntelliCap(®) Device to Quantify Regional Drug Absorption in Human GI Tract Using Diltiazem as Model Drug

Typically, colonic absorption of a drug is mandatory for a sustained release formulation to hold the drug’s plasma level for more than 12 or 24 h above the minimum therapeutic plasma concentration (efficacy). According to Drugs@FDA, only 7.4% of the oral drugs are extended release forms probably sho...

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Detalles Bibliográficos
Autores principales: Becker, Dieter, Zhang, Jin, Heimbach, Tycho, Penland, Robert C., Wanke, Christoph, Shimizu, Jeff, Kulmatycki, Kenneth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245429/
https://www.ncbi.nlm.nih.gov/pubmed/25023947
http://dx.doi.org/10.1208/s12249-014-0172-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245429/
https://www.ncbi.nlm.nih.gov/pubmed/25023947
http://dx.doi.org/10.1208/s12249-014-0172-1

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