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Simplifying complexity: genetically resculpting glycosphingolipid synthesis pathways in mice to reveal function
Glycosphingolipids (GSLs) are a group of plasma-membrane lipids notable for their extremely diverse glycan head groups. The metabolic pathways for GSLs, including the identity of the biosynthetic enzymes needed for synthesis of their glycans, are now well understood. Many of their cellular functions...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245496/ https://www.ncbi.nlm.nih.gov/pubmed/25351657 http://dx.doi.org/10.1007/s10719-014-9563-5 |