PMI: A ΔΨ(m) Independent Pharmacological Regulator of Mitophagy

Mitophagy is central to mitochondrial and cellular homeostasis and operates via the PINK1/Parkin pathway targeting mitochondria devoid of membrane potential (ΔΨ(m)) to autophagosomes. Although mitophagy is recognized as a fundamental cellular process, selective pharmacologic modulators of mitophagy...

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Detalles Bibliográficos
Autores principales: East, Daniel A., Fagiani, Francesca, Crosby, James, Georgakopoulos, Nikolaos D., Bertrand, Hélène, Schaap, Marjolein, Fowkes, Adrian, Wells, Geoff, Campanella, Michelangelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Resource
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245710/
https://www.ncbi.nlm.nih.gov/pubmed/25455860
http://dx.doi.org/10.1016/j.chembiol.2014.09.019

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