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Synthesis of a heparin-related GlcN–IdoA sulfation-site variable disaccharide library and analysis by Raman and ROA spectroscopy
Synthesis of an array of differentially sulfated GlcN–IdoA disaccharides, accessible on good scale, directly from l-iduronate components is described. These are specifically directed to provide the sulfation variability at the key most common biologically relevant sulfation-variable l-IdoA O-2 and d...
Autores principales: | Miller, Gavin J., Hansen, Steen U., Baráth, Marek, Johannessen, Christian, Blanch, Ewan W., Jayson, Gordon C., Gardiner, John M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245711/ https://www.ncbi.nlm.nih.gov/pubmed/25457609 http://dx.doi.org/10.1016/j.carres.2014.06.026 |
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