Computational approach for calculating the probability of eukaryotic translation initiation from ribo-seq data that takes into account leaky scanning

BACKGROUND: Ribosome profiling (ribo-seq) provides experimental data on the density of elongating or initiating ribosomes at the whole transcriptome level that can be potentially used for estimating absolute levels of translation initiation at individual Translation Initiation Sites (TISs). These ab...

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Detalles Bibliográficos
Autores principales: Michel, Audrey M, Andreev, Dmitry E, Baranov, Pavel V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245810/
https://www.ncbi.nlm.nih.gov/pubmed/25413677
http://dx.doi.org/10.1186/s12859-014-0380-4

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